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CEF Seminar – Prof Luisa Torsi
January 22 @ 1:00 pm - 2:00 pm
Join us on Friday 22 at 13.00 (UK time)!
Prof. Luisa Torsi Università degli Studi di Bari
Ultimately Sensitive Potentiometric Organic Bioelectronic Sensors
The interest in ultra-highly sensitive clinical assays, stems from the foreseen advantages that are connected with technologies capable of tracking a biomarker down to the physical limit. This can open to the possibility of achieving the earliest possible diagnosis. Organic field-effect transistors are operated in an electrolyte immobilizing a layer of bio-recognition elements on a large area interface, that that enables one to selectively, detect both proteins and genomic analytes at the single molecule level. These features along with the foreseen low-cost for their production, make them very appealing for point-ofcare biomedical applications. This lecture aims at providing a systematic comparison between the potentiometric sensors and their organic bioelectronic transistors counterparts, showing why the latter can sense at the single-molecule level. Moreover, materialscience and devices-operational aspects underpinning the sensing-principles of the assessed technologies critically prioritizing them according to scrutinized figures-of-merit such as limit-of-detection, need for a labelling-step and feasibility to assay biofluids.